Myriad Genetics
MYGNNASDAQUSD
- Source valuation snapshot. Not a live recalculation.
- Latest filed annual earnings; price snapshot date unavailable. Not forward P/E.
- Diluted earnings per share from the latest filed annual.
- $5.67 Prior regular-session close from the quote source.
- $5.56–$5.86 Regular-session low and high so far today.
- 1.4M Regular-session shares traded · Nov 11, 4:00 PM ET.
- Not yet confirmed The company has not confirmed its next report date. Reported quarters are available in the chart’s Earnings view.
- $2.74–$8.09 52-week trading low and high returned by the quote source.
Understand the Business
Why the Stock Moved
Period-matched expectations history is not yet available. Current metrics are not a substitute for a historical explanation.
The core investment thesis
Own MYGN if its clinical genetics franchise can keep winning reimbursed physician-ordered testing while management turns a roughly 70% gross-margin revenue base into durable cash generation rather than recurring GAAP losses.
MYGN price history
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Investment thesis
What must happen next
Physician and payer recognition of Myriad’s genetic tests as clinically useful keeps demand converting into reimbursed orders, rather than being displaced by cheaper generic sequencing panels.HoldingMateriality: High
GAAP annual revenue was $824.5 million in FY2025, still materially above $678.4 million in FY2022. If this holds, revenue can recover and the fixed-cost lab model has something to scale; if it breaks, the turnaround loses its top-line engine.
Watch: Major commercial payers or Medicare contractors narrow medical-necessity policies, impose prior authorization, or reduce reimbursement for hereditary cancer, reproductive health, oncology, or pharmacogenomic testing.
Supporting sources
Source notes are factual paraphrases; read the original disclosures below.
GAAP annual revenue was $824.5 million in FY2025, still materially above $678.4 million in FY2022.
Open source ↗Myriad’s value must come from clinically trusted interpretation, payer access, and workflow integration, because raw sequencing capacity alone is not enough to defend pricing in molecular diagnostics.StrengtheningMateriality: High
GAAP annual gross profit was $576.6 million in FY2025 on $824.5 million of revenue, implying a roughly 70% GAAP gross margin. Sustained gross profit indicates the franchise is not fully commoditized; erosion would signal declining pricing power and weaker eventual earnings.
Watch: Payers adopt reference pricing or reimbursement cuts that treat genetic panels as interchangeable commodity tests.
Supporting sources
Source notes are factual paraphrases; read the original disclosures below.
GAAP annual gross profit was $576.6 million in FY2025 on $824.5 million of revenue, implying a roughly 70% GAAP gross.
Open source ↗The investment case depends on management converting Myriad’s high gross-margin lab revenue into operating leverage through billing, automation, sales-force productivity, and cost discipline, not just adding more test volume.WeakeningMateriality: Medium
GAAP annual operating loss improved from negative $257.4 million in FY2023 to negative $123.5 million in FY2024. If operating leverage appears, shareholder value can compound from the existing revenue base; if not, growth may continue to destroy capital.
Watch: Sales, marketing, R&D, lab operations, billing infrastructure, or restructuring costs remain structurally too high for the revenue base.
Supporting sources
Source notes are factual paraphrases; read the original disclosures below.
GAAP annual operating loss improved from negative $257.4 million in FY2023 to negative $123.5 million in FY2024.
Open source ↗The turnaround needs Myriad’s operations to fund themselves; otherwise, even clinically valuable testing could require dilutive equity or balance-sheet stress before profitability is proven.HoldingMateriality: Medium
GAAP annual operating cash flow improved from negative $110.9 million in FY2023 to negative $8.7 million in FY2024 and positive $1.8 million in FY2025. Self-funding preserves per-share upside, while renewed cash burn shifts value from shareholders to capital providers.
Watch: A payer reimbursement disruption causes receivables build, denials, or lower collections before revenue fully reflects the problem.
Supporting sources
Source notes are factual paraphrases; read the original disclosures below.
GAAP annual operating cash flow improved from negative $110.9 million in FY2023 to negative $8.7 million in FY2024 and positive.
Open source ↗Myriad has a financing window to execute the turnaround, but that window is finite unless cash flow improvement persists and losses narrow.StrengtheningMateriality: Medium
Cash and equivalents were $149.6 million at FY2025 year-end. Enough liquidity gives management time to repair margins; a shrinking cushion would reduce strategic flexibility and raise dilution risk.
Watch: A return to sustained operating cash burn from reimbursement pressure or cost overruns reduces the cash runway.
Supporting sources
Source notes are factual paraphrases; read the original disclosures below.
Cash and equivalents were $149.6 million at FY2025 year-end.
Open source ↗
Full investment case & evidence
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Original research
Physician and payer recognition of Myriad’s genetic tests as clinically useful keeps demand converting into reimbursed orders, rather than being displaced by cheaper generic sequencing panels. If this holds, revenue can recover and the fixed-cost lab model has something to scale; if it breaks, the turnaround loses its top-line engine.
Myriad’s value must come from clinically trusted interpretation, payer access, and workflow integration, because raw sequencing capacity alone is not enough to defend pricing in molecular diagnostics. Sustained gross profit indicates the franchise is not fully commoditized; erosion would signal declining pricing power and weaker eventual earnings.
The investment case depends on management converting Myriad’s high gross-margin lab revenue into operating leverage through billing, automation, sales-force productivity, and cost discipline, not just adding more test volume. If operating leverage appears, shareholder value can compound from the existing revenue base; if not, growth may continue to destroy capital.
The turnaround needs Myriad’s operations to fund themselves; otherwise, even clinically valuable testing could require dilutive equity or balance-sheet stress before profitability is proven. Self-funding preserves per-share upside, while renewed cash burn shifts value from shareholders to capital providers.
Myriad has a financing window to execute the turnaround, but that window is finite unless cash flow improvement persists and losses narrow. Enough liquidity gives management time to repair margins; a shrinking cushion would reduce strategic flexibility and raise dilution risk.
All standing thesis claims
Original report summary
its clinical genetics franchise can keep winning reimbursed physician-ordered testing while management turns a roughly 70% gross-margin revenue base into durable cash generation rather than recurring GAAP losses.
Bull case and bear case
Bull case and bear case for Myriad Genetics
Where the evidence on Myriad Genetics disagrees: Mixed on the latest evidence (Oct 13, 2026). Of its 5 thesis points, 2 strengthening, 2 holding and 1 weakening.
Bull case: what the evidence supports
Physician and payer recognition of Myriad’s genetic tests as clinically useful keeps demand converting into reimbursed orders, rather than being displaced by cheaper generic sequencing panels.
Myriad’s value must come from clinically trusted interpretation, payer access, and workflow integration, because raw sequencing capacity alone is not enough to defend pricing in molecular diagnostics.
The turnaround needs Myriad’s operations to fund themselves; otherwise, even clinically valuable testing could require dilutive equity or balance-sheet stress before profitability is proven.
Myriad has a financing window to execute the turnaround, but that window is finite unless cash flow improvement persists and losses narrow.
Bear case: what the evidence questions
The investment case depends on management converting Myriad’s high gross-margin lab revenue into operating leverage through billing, automation, sales-force productivity, and cost discipline, not just adding more test volume.
Thesis-Break Engine
What has broken in Myriad Genetics’s thesis
Each break OptimistFi flagged on Myriad Genetics, dated — with what has historically followed the same kind of break across the market, not a forecast for Myriad Genetics.
- CEO / officer changecondition set before this filing
Across all companies, this kind of break has happened 16,849 times before. Those stocks trailed comparable companies by a median of 2% over the next six months, and 38% of them trailed it by 10 points or more.
- Analyst downgradecondition set before this filing
Across all companies, this kind of break has happened 12,641 times before. Those stocks trailed comparable companies by a median of 1% over the next six months, and 33% of them trailed it by 10 points or more.
Several kinds of break have stacked on Myriad Genetics at once. A cluster is a stronger read than any one signal alone.
MARKET + FINANCIAL SNAPSHOT
The numbers behind the thesis
What Changed
- MixedDirector or principal officer change.
Myriad Genetics filed an SEC 8-K on 2026-10-09: Director or principal officer change. It is a dated development that tests the current thesis.
- MixedDirector or principal officer change.
Myriad Genetics filed an SEC 8-K on 2026-09-16: Director or principal officer change. It is a dated development that tests the current thesis.
- MixedReported results of operations (earnings release).
Myriad Genetics filed an SEC 8-K on 2026-07-30: Reported results of operations (earnings release). It is a dated development that tests the current thesis.
Risks / falsifiers
What could break the thesis
- Major commercial payers or Medicare contractors narrow medical-necessity policies, impose prior authorization, or reduce reimbursement for hereditary cancer, reproductive health, oncology, or pharmacogenomic testing.
- Payers adopt reference pricing or reimbursement cuts that treat genetic panels as interchangeable commodity tests.
- Sales, marketing, R&D, lab operations, billing infrastructure, or restructuring costs remain structurally too high for the revenue base.
- A payer reimbursement disruption causes receivables build, denials, or lower collections before revenue fully reflects the problem.
- A return to sustained operating cash burn from reimbursement pressure or cost overruns reduces the cash runway.
MYGN news
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Financial statements
MYGN income statement
Annual filed results · USD · Oldest to newest. Margins are calculated from the reported figures.
