Codexis
CDXSNASDAQUSD
- Source valuation snapshot. Not a live recalculation.
- Latest filed annual earnings; price snapshot date unavailable. Not forward P/E.
- Diluted earnings per share from the latest filed annual.
- $1.00 Prior regular-session close from the quote source.
- $0.95–$1.02 Regular-session low and high so far today.
- 1.7M Regular-session shares traded · Nov 11, 4:00 PM ET.
- Not yet confirmed The company has not confirmed its next report date. Reported quarters are available in the chart’s Earnings view.
- $0.95–$2.98 52-week trading low and high returned by the quote source.
Understand the Business
Why the Stock Moved
Period-matched expectations history is not yet available. Current metrics are not a substitute for a historical explanation.
The core investment thesis
Own CDXS if its enzyme-engineering platform becomes a repeatable, high-gross-profit solution for therapeutics manufacturing rather than a lumpy development-services business.
CDXS price history
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Investment thesis
What must happen next
Therapeutics manufacturers keep adopting Codexis technology because specialized enzymes solve process bottlenecks that are hard to address with conventional chemistry or generic enzyme suppliers.HoldingMateriality: High
GAAP annual revenue was $70.4 million in FY2025, up from $59.3 million in FY2024. If Codexis is designed into more customer processes, revenue can become more durable; if customers bypass it, the platform remains too small and lumpy.
Watch: Large pharmaceutical customers build internal enzyme-engineering teams and stop outsourcing key process-development work.
Supporting sources
Source notes are factual paraphrases; read the original disclosures below.
GAAP annual revenue was $70.4 million in FY2025, up from $59.3 million in FY2024.
Open source ↗Codexis retains pricing power when its engineered enzymes or process know-how are tied to high-value therapeutics manufacturing outcomes rather than sold as commodity inputs.StrengtheningMateriality: High
Derived GAAP annual gross profit was $61.0 million in FY2025 on $70.4 million of GAAP annual revenue. High gross profit would support a platform model; margin erosion would signal weaker differentiation and less economic value capture.
Watch: Customers require Codexis to transfer process know-how for fixed fees, limiting ongoing economics.
Supporting sources
Source notes are factual paraphrases; read the original disclosures below.
Derived GAAP annual gross profit was $61.0 million in FY2025 on $70.4 million of GAAP annual revenue.
Open source ↗Management’s narrower focus on therapeutics manufacturing lets Codexis convert platform work into better cash economics instead of funding too many scientific programs ahead of demand.StrengtheningMateriality: Medium
GAAP annual operating cash flow improved to negative $19.4 million in FY2025 from negative $49.4 million in FY2024. If operating cash burn keeps narrowing, the company can fund the adoption cycle; if focus slips, shareholders face dilution or strategic dependence.
Watch: Codexis launches or re-expands platform programs that require material R&D spending before signed customer demand.
Supporting sources
Source notes are factual paraphrases; read the original disclosures below.
GAAP annual operating cash flow improved to negative $19.4 million in FY2025 from negative $49.4 million in FY2024.
Open source ↗Codexis has enough balance-sheet runway only if customer adoption and spending discipline continue to reduce cash burn before the next major financing need.HoldingMateriality: Medium
Cash was $50.8 million at FY2025 year-end, up from $19.3 million at FY2024 year-end. A sufficient runway lets owners participate in platform upside; an external financing need could transfer value to new investors or creditors.
Watch: Customer conversions take longer than the cash runway implied by current operating burn.
Supporting sources
Source notes are factual paraphrases; read the original disclosures below.
Cash was $50.8 million at FY2025 year-end, up from $19.3 million at FY2024 year-end.
Open source ↗Codexis can scale through specialized know-how and partner adoption rather than building a large labor-intensive organization.HoldingMateriality: Medium
The company had 146 full-time and part-time employees worldwide as of December 31, 2025. If the model scales with a small expert team, incremental revenue can have attractive economics; if commercialization requires a much larger organization, margin and cash-flow upside shrink.
Watch: Key enzyme-engineering scientists or commercial leaders leave and are difficult to replace.
Supporting sources
Source notes are factual paraphrases; read the original disclosures below.
The company had 146 full-time and part-time employees worldwide as of December 31, 2025.
Open source ↗
Full investment case & evidence
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Original research
Therapeutics manufacturers keep adopting Codexis technology because specialized enzymes solve process bottlenecks that are hard to address with conventional chemistry or generic enzyme suppliers. If Codexis is designed into more customer processes, revenue can become more durable; if customers bypass it, the platform remains too small and lumpy.
Codexis retains pricing power when its engineered enzymes or process know-how are tied to high-value therapeutics manufacturing outcomes rather than sold as commodity inputs. High gross profit would support a platform model; margin erosion would signal weaker differentiation and less economic value capture.
Management’s narrower focus on therapeutics manufacturing lets Codexis convert platform work into better cash economics instead of funding too many scientific programs ahead of demand. If operating cash burn keeps narrowing, the company can fund the adoption cycle; if focus slips, shareholders face dilution or strategic dependence.
Codexis has enough balance-sheet runway only if customer adoption and spending discipline continue to reduce cash burn before the next major financing need. A sufficient runway lets owners participate in platform upside; an external financing need could transfer value to new investors or creditors.
Codexis can scale through specialized know-how and partner adoption rather than building a large labor-intensive organization. If the model scales with a small expert team, incremental revenue can have attractive economics; if commercialization requires a much larger organization, margin and cash-flow upside shrink.
All standing thesis claims
Original report summary
its enzyme-engineering platform becomes a repeatable, high-gross-profit solution for therapeutics manufacturing rather than a lumpy development-services business.
Bull case and bear case
Bull case and bear case for Codexis
Where the evidence on Codexis stands: Holding on the latest evidence (Nov 12, 2026). Of its 5 thesis points, 2 strengthening and 3 holding.
Bull case: what the evidence supports
Therapeutics manufacturers keep adopting Codexis technology because specialized enzymes solve process bottlenecks that are hard to address with conventional chemistry or generic enzyme suppliers.
Codexis retains pricing power when its engineered enzymes or process know-how are tied to high-value therapeutics manufacturing outcomes rather than sold as commodity inputs.
Management’s narrower focus on therapeutics manufacturing lets Codexis convert platform work into better cash economics instead of funding too many scientific programs ahead of demand.
Codexis has enough balance-sheet runway only if customer adoption and spending discipline continue to reduce cash burn before the next major financing need.
Codexis can scale through specialized know-how and partner adoption rather than building a large labor-intensive organization.
Bear case: what would count against it
Large pharmaceutical customers build internal enzyme-engineering teams and stop outsourcing key process-development work.
Customers require Codexis to transfer process know-how for fixed fees, limiting ongoing economics.
Codexis launches or re-expands platform programs that require material R&D spending before signed customer demand.
Thesis-Break Engine
Thesis-break watch · Codexis
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MARKET + FINANCIAL SNAPSHOT
The numbers behind the thesis
What Changed
- MixedEntered a material definitive agreement.
Codexis filed an SEC 8-K on 2026-11-10: Entered a material definitive agreement. It is a dated development that tests the current thesis.
- MixedReported results of operations (earnings release).
Codexis filed an SEC 8-K on 2026-08-11: Reported results of operations (earnings release). It is a dated development that tests the current thesis.
- MixedOther material event.
Codexis filed an SEC 8-K on 2026-07-27: Other material event. It is a dated development that tests the current thesis.
Risks / falsifiers
What could break the thesis
- Large pharmaceutical customers build internal enzyme-engineering teams and stop outsourcing key process-development work.
- Customers require Codexis to transfer process know-how for fixed fees, limiting ongoing economics.
- Codexis launches or re-expands platform programs that require material R&D spending before signed customer demand.
- Customer conversions take longer than the cash runway implied by current operating burn.
- Key enzyme-engineering scientists or commercial leaders leave and are difficult to replace.
CDXS news
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Financial statements
CDXS income statement
Annual filed results · USD · Oldest to newest. Margins are calculated from the reported figures.
